I Never have done this before , but my guess is that you "only" have to route the stereo signal out of the pc , to an amp ...
(anyway ... this is how i should have done it ... )
I didnt found any related sites yet , but im almost 99% sure its been done the way i explained ... (lol , its probably that 1% who kills me though ..lol)
But i can advise you to have a google search ...
http://www.soundonsound.com/sos/dec0...ntech_1206.htm
The page above has some nice tips and tricks on using reason live ...
Greetzzzzzzz and good luck !!!